nanomake-L™ is India’s first automated microfluidic platform for precise and reproducible nano-formulation at the lab scale.
nanomake utilizes both, single-use and multi-use microfluidic chips to enable reproducible scale-up of nano formulations, such as mRNA-lipid nanoparticles (LNPs), polymeric nanoparticles, liposomes and emulsions while preserving their critical quality attributes. The instrument is based on controlled microfluidic mixing technology, ensures the production of uniform and reproducible high-quality nanoparticles.
nanomake-L™ costs 40–60% less than imported microfluidic systems. Further, it incurs lower maintenance costs due to locally available components and technical support.
Unlike conventional manual or semi-automated systems, nanomake-L™ operates with zero manual intervention, automating critical parameters such as priming, in-line dilution, flow rate, and mixing ratios.
Unlike single-use systems, nanomake-L™ offers reusable, customizable microfluidic chips with different internal volumes and Material of Construction (MOC) options, making it adaptable for various applications.
Our proprietary architecture enhances precision, ensuring uniform nano-formulation, critical for drug development and delivery.
Operates at 100 µL/min to 50 mL/min, enabling lab-scale and scale-up studies.
The system includes an in-built cleaning mechanism, ensuring chip reusability while reducing cross-contamination and lowering operational costs.
Supports multiple syringe sizes (500 µL – 10 mL) and allows for the use of multiple nanomaterials for synthesis of lipid nanoparticles (LNPs), polymeric nanoparticles, liposomes and emulsions.